Article
DNA-ploidy in advanced gastric carcinoma is less heterogeneous than in early gastric cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2004
Osterheld Maria-Chiara, Caron Liette, Demierre Mireille, Laurini Ricardo, Bosman F T
Abstract excerpt
This analysis of DNA-ploidy heterogeneity in advanced gastric carcinomas is consistent with the hypothesis of the emergence of a single aneuploid cell clone as a crucial mechanism in the progression from early gastric carcinoma to advanced gastric cancer. The prognostic value of DNA-ploidy in gastric cancers has been a matter of controversy. Tumour DNA-ploidy heterogeneity, the presence within the same tumour of...
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