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Article

Single-nucleotide polymorphism genotyping on optical thin-film biosensor chips.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 2003

Zhong Xiao-Bo, Reynolds Robert, Kidd Judith R, Kidd Kenneth K, Jenison Robert, Marlar Richard A, Ward David C

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) constitute the bulk of human genetic variation and provide excellent markers to identify genetic factors contributing to complex disease susceptibility. A rapid, sensitive, and inexpensive assay is important for large-scale SNP scoring. Here we report the development of a multiplex SNP detection system using silicon chips coated to create a thin-film optical biosensor....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 17

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Source

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Identifiers

PMID: 12975525
DOI: 10.1073/pnas.1934783100
PMCID: PMC208797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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