Article
Silicon-based biosensors for rapid detection of protein or nucleic acid targets.
Clinical chemistry - 1 Oct 2001
Jenison R, La H, Haeberli A, Ostroff R, Polisky B
Abstract excerpt
BACKGROUND: We developed a silicon-based biosensor that generates visual, qualitative results or quantitative results for the detection of protein or nucleic acid targets in a multiplex format. METHODS: Capture probes were immobilized either passively or covalently on the optically coated surface of the biosensor. Intermolecular interactions of the immobilized capture probe with specific target molecules were...
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