Article
Chip-based genotyping by mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America - 31 Aug 1999
Tang K, Fu D J, Julien D, Braun A, Cantor C R, Köster H
Abstract excerpt
Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
