Article
The role of the eNOS G894T and T-786C gene polymorphism in the development of ascites in cirrhosis.
European review for medical and pharmacological sciences - 1 Nov 2016
Yildirim O, Yigit A, Seckin Y, Yesilada E, Gulbay G, Cagin Y F, Aksungur Z, Bilgic Y, Türkoz Y, Yologlu S
Abstract excerpt
OBJECTIVE: Increased nitric oxide (NO) production in cirrhotic patients causes splanchnic vasodilation, leading to the development of the hyperdynamic circulatory syndrome. One factor that influences plasma NO concentration is eNOS gene polymorphism; consequently, the aim of this study was to investigate whether the eNOS gene G894T and T-786C polymorphisms play any role in the development of ascites in such...
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