Article
[The association between polymorphism of endothelial nitric oxide synthase gene and cirrhotic portal hypertension].
Zhonghua yi xue za zhi - 10 Jul 2003
Cheng Yuan-qiao, Lin Ju-sheng, Liao Jia-zhi, Liang Kuo-huan, Xiong Ping
Abstract excerpt
OBJECTIVE: To study whether the liver cirrhosis and portal hypertension are associated with a -786T-->C mutation at promoter and VNTR polymorphism in intron 4 and a 894 G-->T mutation at exon 7 of the eNOS. METHODS: A case control study of 106 patients with liver cirrhosis due to HBV was performed in comparison with 108 controls with the help of PCR-SSCP or RFLP. RESULTS: There was no difference in the gene...
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