Article
Increased gene and protein expression of the novel eNOS regulatory protein NOSTRIN and a variant in alcoholic hepatitis.
Gastroenterology - 1 Jun 2007
Mookerjee Rajeshwar P, Wiesenthal Anja, Icking Ann, Hodges Stephen J, Davies Nathan A, Schilling Kirstin, Sen Sambit, Williams Roger, Novelli Marco, Müller-Esterl Werner, Jalan Rajiv
Abstract excerpt
BACKGROUND & AIMS: Increased intrahepatic resistance in cirrhosis is associated with reduced endothelial NO synthase (eNOS) activity and exacerbated by superimposed inflammation. NOSTRIN induces intracellular translocation of eNOS and reduces NO generation. Our aims were to quantify and compare h...
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