Article
[Polymorphism of NOS2A promoter -969(G>C) is associated with portal hypertension of liver cirrhosis].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2004
Cheng Yuan-qiao, Wang Wen-qi, Lin Ju-sheng, Xiong Ping, Jiang Xiao-dan
Abstract excerpt
OBJECTIVE: To determine whether polymorphism of NOS2A promoter -969G>C is associated with the portal hypertension of liver cirrhosis. METHODS: A case control study covering 106 patients with liver cirrhosis due to hepatitis B virus(HBV) in comparison with 108 controls was performed using PCR-restriction fragment length polymorphism. The NOS2A mRNA and protein expression in liver cirrhosis tissues were detected by...
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