Article
Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (Dipeptidyl-peptidase IV; CD26) gene in rats.
Regulatory peptides - 15 Sept 2003
Karl Tim, Chwalisz Wojciech T, Wedekind Dirk, Hedrich Hans J, Hoffmann Torsten, Jacobs Roland, Pabst Reinhard, von Hörsten Stephan
Abstract excerpt
Dipeptidyl-peptidase IV (DPPIV) is involved in endocrine and immune functions via cleavage of regulatory peptides with a N-terminal proline or alanine such as incretins, neuropeptide Y, or several chemokines. So far no systematic investigations on the localization and transmission of the Dpp4 gene or the natural variations of DPPIV-like enzymatic function in different rat strains have been conducted. Here we...
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