Article
Nucleotide sequence of endothelin-B receptor gene reveals origin of piebald mutation in laboratory mouse.
Experimental animals - 1 Oct 1998
Kumagai T, Wada A, Tsudzuki M, Nishimura M, Kunieda T
Abstract excerpt
Piebald (Ednrbs) is a coat color mutation of laboratory mice caused by a decreased expression of endothelin-B receptor gene (Ednrb). The IITES and JF1 mouse strains, whose origins are believed to be different from those of the common laboratory inbred strains, also show a phenotype similar to Ednrbs. In the present study, we found that the nucleotide sequence of the Ednrb gene of the IITES and JF1 mice is...
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