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Article

Regulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells.

Oncogene - 11 Sept 2003

Heckman Caroline A, Wheeler Melissa A, Boxer Linda M

Abstract excerpt

In follicular lymphomas with the t(14;18) translocation, there is increased expression of the bcl-2 gene, which is dependent upon regulatory elements within the bcl-2 5' flanking region and the immunoglobulin heavy-chain gene enhancers. We found that t(14;18) lymphomas expressed C/EBPalpha, which is not normally expressed in B lymphocytes. Expression of C/EBPalpha increased bcl-2 expression, and two regions of...

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Source

Identifiers

PMID: 12970736
DOI: 10.1038/sj.onc.1206639

Genes

EBP
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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