Article
NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells.
Oncogene - 30 May 2002
Heckman Caroline A, Mehew John W, Boxer Linda M
Abstract excerpt
The t(14;18) translocation, which is characteristic of follicular lymphoma, results in the overexpression of the bcl-2 gene dependent upon regulatory elements within the bcl-2 5' flanking region and the immunoglobulin heavy chain gene enhancers. Conflicting evidence exists on the effects of NF-ka...
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