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Article

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

Science (New York, N.Y.) - 12 Sept 2003

Yamashita Yukiko M, Jones D Leanne, Fuller Margaret T

Abstract excerpt

Stem cell self-renewal can be specified by local signals from the surrounding microenvironment, or niche. However, the relation between the niche and the mechanisms that ensure the correct balance between stem cell self-renewal and differentiation is poorly understood. Here, we show that dividing...

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Identifiers

PMID: 12970569
DOI: 10.1126/science.1087795

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12970569-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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