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Article

Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine.

Cell stem cell - 4 May 2017

Lucchetta Elena M, Ohlstein Benjamin

Abstract excerpt

Organ fitness depends on appropriate maintenance of stem cell populations, and aberrations in functional stem cell numbers are associated with malignancies and aging. Symmetrical division is the best characterized mechanism of stem cell replacement, but other mechanisms could also be deployed, particularly in situations of high stress. Here, we show that after severe depletion, intestinal stem cells (ISCs) in the...

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Identifiers

PMID: 28343984
DOI: 10.1016/j.stem.2017.02.012
PMCID: PMC5419863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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