Article
Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study.
Respiratory research - 4 Feb 2013
Moreno-Macías Hortensia, Dockery Douglas W, Schwartz Joel, Gold Diane R, Laird Nan M, Sienra-Monge Juan J, Del Río-Navarro Blanca E, Ramírez-Aguilar Matiana, Barraza-Villarreal Albino, Li Huiling, London Stephanie J, Romieu Isabelle
Abstract excerpt
BACKGROUND: We previously reported that asthmatic children with GSTM1 null genotype may be more susceptible to the acute effect of ozone on the small airways and might benefit from antioxidant supplementation. This study aims to assess the acute effect of ozone on lung function (FEF(25-75)) in asthmatic children according to dietary intake of vitamin C and the number of putative risk alleles in three antioxidant...
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