Article

Non-invasive in vivo bidirectional magnetogenetic modulation of pain circuits

2025-03-19

Abstract excerpt

Primary nociceptors in the dorsal root ganglion (DRG) receive sensory information from discrete parts of the body and are responsible for initiating signaling events that in supraspinal regions will be interpreted as physiological or pathological pain. Genetic, pharmacologic and electric neuromodulation of nociceptor activity in freely moving non-transgenic animals has been shown to be challenging due to many fact...

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Literature Corpus work: 39bcc0be-e056-5c03-81ba-2efa01b3bf95
DOI: 10.1101/2025.03.18.644041

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