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Article

Mutation of BAD within the BH3 domain impairs its phosphorylation-mediated regulation.

FEBS letters - 11 Sept 2003

Adachi M, Zhang Yu Bin, Imai K

Abstract excerpt

Pro-apoptotic functions of the BH3-only protein BAD are negatively regulated by survival signal-mediated phosphorylation at several serine residues. Recently, we found that the mutant BAD (BADD119G) with an amino acid substitution of Asp (Asp119 to Gly) within the BH3 domain displays strong pro-a...

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Source

Identifiers

PMID: 12965220
DOI: 10.1016/s0014-5793(03)00915-3

Genes

BAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12965220-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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