Article
Forced expression of cyclin D1 does not compensate for Id2 deficiency in the mammary gland.
FEBS letters - 11 Sept 2003
Mori Seiichi, Inoshima Kenji, Shima Yoko, Schmidt Emmett V, Yokota Yoshifumi
Abstract excerpt
Id2 and cyclin D1 share several biological activities, including inhibition of differentiation, stimulation of the G1-S transition in the cell cycle and stimulation of tumorigenesis. Mammary glands of Id2(-/-) mice display severely impaired lobulo-alveolar development during pregnancy, similarly...
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