Article
Robust levels of long-term multilineage reconstitution in the absence of stem cell self-replication in W/Wv mice transplanted with purified stem cells.
Journal of hematotherapy & stem cell research - 1 Aug 2003
Migliaccio Anna Rita, Lorenzini Rodolfo, Vannucchi Alessandro M, Spangrude Gerald J, Migliaccio Giovanni
Abstract excerpt
Isolation of primitive blood stem cells by different methods results in cell populations with distinct biological activities. This study was aimed at resolving differences in the frequency of multilineage reconstituting cells (MRC) and their precursors (pMRC) in cell populations isolated by positive selection for Sca-1 compared to those isolated by negative selection for 15-1.1. Separation of wheat germ...
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