Article
In vivo expansion of purified hematopoietic stem cells transplanted in nonablated W/Wv mice.
Experimental hematology - 1 Nov 1999
Migliaccio A R, Carta C, Migliaccio G
Abstract excerpt
We have evaluated the in vivo amplification potential of purified murine hematopoietic stem cells, identified as Wheat Germ Agglutinin+ (WGA+), 15-1.1(-) , Rhodamine 123 Dull (Rho-dull) cells, by serial transplantation into stem cell defective nonmyeloablated W/Wv mice. C57BL Rho-dull cells (250/ 500 cells/mouse) permanently engrafted nonablated W/Wv mice as defined by the presence of > 95% red and > 20% white...
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