Article
No association between a putative functional promoter variant in the dopamine beta-hydroxylase gene and schizophrenia.
Psychiatric genetics - 1 Sept 2003
Jönsson Erik G, Abou Jamra Rami, Schumacher Johannes, Flyckt Lena, Edman Gunnar, Forslund Kaj, Mattila-Evenden Marja, Rylander Gunnar, Asberg Marie, Bjerkenstedt Lars, Wiesel Frits-Axel, Propping Peter, Cichon Sven, Nöthen Markus M, Sedvall Göran C
Abstract excerpt
OBJECTIVE: Disturbances in catecholamine transmission have been implicated in schizophrenia. Dopamine beta-hydroxylase catalyses the conversion of dopamine to norepinephrine in noradrenergic cells. We attempted to investigate a putative functional promoter polymorphism in the dopamine beta-hydrox...
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