Article
Schizophrenia and the dopamine-beta-hydroxylase gene: results of a linkage and association study.
Psychiatric genetics - 1 Jan 1996
Meszaros K, Lenzinger E, Füreder T, Hornik K, Willinger U, Stompe T, Heiden A M, Resinger E, Fathi N, Gerhard E, Fuchs K, Miller-Reiter E, Pfersmann V, Sieghart W, Aschauer H N, Kasper S
Abstract excerpt
Alterations in dopamine neurotransmission and disturbed norepinephrine activity have been implicated in the pathogenesis of schizophrenia. We considered the dopamine-beta-hydroxylase (DBH) gene located on the long arm of chromosome 9 (9q34.3) as a candidate gene for schizophrenia. DBH catalyzes the synthesis of norepinephrine from dopamine in noradrenergic neurons. In addition to DBH we used in the linkage study...
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