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Article

Case-control and linkage disequilibrium studies of the tryptophan hydroxylase gene polymorphisms and major depressive disorder.

Psychiatric genetics - 1 Sept 2003

Tan Ene-choo, Chan Angelina O M, Tan Chay-Hoon, Mahendran Rathi, Wang Adrian, Chua Hong-Choon

Abstract excerpt

OBJECTIVES: Alterations in the level of the serotonin, serotonin uptake and the number of binding sites have been linked to affective illness. We investigated the association of tryptophan hydroxylase gene polymorphisms and unipolar depression in a case-control study design. METHODS: Patients and ethnically matched controls were genotyped for three polymorphisms of the tryptophan hydroxylase gene. RESULTS...

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PMID: 12960746
DOI: 10.1097/00041444-200309000-00003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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