Article
Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jun 1996
Hartzog G A, Basrai M A, Ricupero-Hovasse S L, Hieter P, Winston F
Abstract excerpt
Spt4p is a nonhistone protein of Saccharomyces cerevisiae that is believed to be required for normal chromatin structure and transcription. In this work we describe the isolation and analysis of a human gene, SUPT4H, that encodes a predicted protein 42% identical to Spt4p. When expressed in S. ce...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Cloning, Molecular
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- HeLa Cells
- Humans
- Hybrid Cells
- Mice
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligodeoxyribonucleotides