Article
Variation of the platelet glycoprotein IIIa PI(A1/A2) allele frequencies in the three ethnic groups of Singapore.
International journal of cardiology - 1 Aug 2003
Lim Jimmy, Lal Suman, Ng Kenneth C, Ng Kheng-Siang, Saha Nilmani, Heng Chew-Kiat
Abstract excerpt
BACKGROUND: Polymorphisms of the glycoprotein IIIa receptor have been shown to be associated with differences in platelet aggregability. The PI(A2) variant of the polymorphism has been reported to be an inherited risk factor for acute coronary events. Although the allele frequency of this polymorphism is well documented in Caucasian populations, studies involving Asian Indians, Malays and Chinese are lacking. We...
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