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Article

The fat facets gene is required for Drosophila eye and embryo development.

Development (Cambridge, England) - 1 Dec 1992

Fischer-Vize J A, Rubin G M, Lehmann R

Abstract excerpt

In a screen for mutations affecting Drosophila eye development, we have identified a gene called fat facets (faf) which is required for cell interactions that prevent particular cells in the developing eye from becoming photoreceptors. Analysis of eyes mosaic for faf+ and faf- cells shows that faf is required in cells near to, but outside, normal developing photoreceptors and also outside of the ectopic...

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Identifiers

PMID: 1295747
DOI: 10.1242/dev.116.4.985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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The fat facets gene is required for Drosophila eye and embryo development.PMID 1295747Read ↗

The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis.Semantic proximity Read ↗

Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development.Semantic proximity Read ↗

Identification of genes that interact with Drosophila liquid facets.Semantic proximity Read ↗

Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development.Semantic proximity Read ↗

The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary.Semantic proximity Read ↗

The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development.Semantic proximity Read ↗

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.Semantic proximity Read ↗

Anterior-posterior axis specification in Drosophila oocytes: identification of novel bicoid and oskar mRNA localization factors.Semantic proximity Read ↗

Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis.Semantic proximity Read ↗

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.Semantic proximity Read ↗

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