Article
Identification of genes that interact with Drosophila liquid facets.
Genetics - 1 Mar 2007
Eun Suk Ho, Lea Kristi, Overstreet Erin, Stevens Samuel, Lee Ji-Hoon, Fischer Janice A
Abstract excerpt
We have performed mutagenesis screens of the Drosophila X chromosome and the autosomes for dominant enhancers of the rough eye resulting from overexpression of liquid facets. The liquid facets gene encodes the homolog of vertebrate endocytic Epsin, an endocytic adapter protein. In Drosophila, Liquid facets is a core component of the Notch signaling pathway required in the signaling cells for ligand endocytosis...
Topics
- Animals
- Auxilins
- Clathrin Heavy Chains
- Cloning, Molecular
- DNA Primers
- Drosophila
- Drosophila Proteins
- Enhancer Elements, Genetic
- Genes, Insect
- Genetic Complementation Test
- Homeodomain Proteins
- Immunohistochemistry
- Microscopy, Electron, Scanning