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Article

P53 gene of chang-liver cells (Atcc-Ccl13) exposed to aflatoxin B1 (Afb): the effect of lysine on mutation at codon 249 of exon 7.

African journal of medicine and medical sciences - 1 Jan 2000

Uwaifo O

Abstract excerpt

The effect of different regimes of lysine-pre treatment on mutation at the 3rd nucleotide base of codon 249 which is located at the 7th exon of p53 gene of Chang-liver cells (CCIL13) exposed to aflatoxin B1 (AFB1) has been investigated. There is an indication of inhibition of 1 ug/ml AFB1--induced mutation by pretreatment of cells for 72 hr with 5-molar fold lysine equivalent of 1 ug/ml AFB1 1 u/g ml AFB1 was the...

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Share to Aflatoxin B1
Share to Carcinoma, Hepatocellular
Share to Cocarcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytotoxicity Tests, Immunologic

Share to Deoxyribonucleases, Type II Site-Specific

Share to Electrophoresis, Agar Gel

Share to Environmental Exposure

Share to Lysine

Source

Identifiers

PMID: 12953991

Genes

CCL13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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