Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Codon 249 mutation in exon 7 of<i>p53</i>gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China

1 Jan 2003

Abstract excerpt

AIM: One of the characteristics of hepatocellular carcinoma (HCC) in Qidong area is the selective mutation resulting in a serine substitution at codon 249 of the p53 gene (1, 20), and it has been identified as a "hotspot" mutation in heptocellular carcinomas occurring in populations exposed to aflatoxin and with high prevalence of hepatitis B virus carriers (2,3,9, 10,16,24). We evaluated in this paper whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Hepatitis B Virus Studies
Share to Hepatocellular Carcinoma Treatment and Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12679912
DOI: 10.3748/wjg.v9.i4.692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Codon 249 mutation in exon 7 of<i>p53</i>gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, ChinaPMID 12679912Read ↗

[Characteristics of high frequency 249 codon mutation of p53 gene in hepatocellular carcinoma in prevalent area of China].Semantic proximity Read ↗

Prospective detection of codon 249 mutations in plasma of hepatocellular carcinoma patientsSemantic proximity Read ↗

Mutations at codon 249 of p53 gene in human hepatocellular carcinomas from Tongan, China.Semantic proximity Read ↗

Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia.Semantic proximity Read ↗

Mutational hotspot in the p53 gene in human hepatocellular carcinomas.Semantic proximity Read ↗

Different frequencies of p53 codon-249 hot-spot mutations in hepatocellular carcinomas in Jiang-su province of China.Semantic proximity Read ↗

Geographic Variation of <i>p53</i> Mutational Profile in Nonmalignant Human LiverSemantic proximity Read ↗

Aberrations of p53 gene in human hepatocellular carcinoma from China.Semantic proximity Read ↗

TP53 R249S mutation detected in circulating tumour DNA is associated with Prognosis of hepatocellular carcinoma patients with or without hepatectomy.Semantic proximity Read ↗

The prevalence of the mutation in codon 249 of the P53 gene in patients with hepatocellular carcinoma (HCC) in Turkey.Semantic proximity Read ↗

Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma.Semantic proximity Read ↗

Polymorphism of XRCC1 and the frequency of mutation in codon 249 of the p53 gene in hepatocellular carcinoma among Guangxi population, China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.