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Article

Higher grade transformation of follicular lymphoma: phenotypic tumor progression associated with diverse genetic lesions.

Seminars in cancer biology - 1 Jun 2003

Lossos Izidore S, Levy Ronald

Abstract excerpt

Higher grade histological transformation of follicular lymphoma (FL) to more aggressive diffuse large B-cell lymphomas (DLBCL) occurs in 10-60% of the cases. Review of the current knowledge of genetic and molecular alterations associated with the higher grade transformation of FCL suggests that the process that leads to clinically and phenotypically similar end-point can occur by functionally diverse genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 12959350
DOI: 10.1016/s1044-579x(03)00015-4

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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