Article
Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe.
Bioscience, biotechnology, and biochemistry - 1 Aug 2003
Onishi Masayuki, Nakamura Yoko, Koga Takako, Takegawa Kaoru, Fukui Yasuhisa
Abstract excerpt
The ste12+ gene of Schizosaccharomyces pombe codes for a phosphatidylinositol (PI) 3-phosphate 5'-kinase, which is required for efficient mating. Suppressor mutants for sterility of ste12Delta cells were screened for. Most of the mutant genes turned out to be recessive. Six genes were cloned and the open reading frames responsible for the suppressor activity were identified. They included genes coding for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.