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Article

Mutations in the pfmdr1, dhfr and dhps genes of Plasmodium falciparum are associated with in-vivo drug resistance in West Papua, Indonesia.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000

Nagesha H S, Din-Syafruddin, Casey G J, Susanti A I, Fryauff D J, Reeder J C, Cowman A F

Abstract excerpt

This study (conducted in 1996-99) examines the association of mutations in pfmdr1, dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes of Plasmodium falciparum with in-vivo drug resistance in West Papua, Indonesia. Initially, 85 patients infected with P. falciparum were treated with chloroquine, of whom 21 were cleared of parasites, 49 had parasitaemias classified as RI, RII or RIII...

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PMID: 11280065
DOI: 10.1016/s0035-9203(01)90329-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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