Intra- and interspecific variation of the CCR5 gene in higher primates.

doi:10.1093/molbev/msg198

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Intra- and interspecific variation of the CCR5 gene in higher primates.

Molecular biology and evolution - 1 Oct 2003

Zhang Yun-wu, Ryder Oliver A, Zhang Ya-ping

Abstract excerpt

We have evaluated the molecular evolution of the chemokine receptor CCR5 in primates. The chemokine receptor CCR5 serves as a major co-receptor for human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) infection. Knowledge of evolution of the CCR5 molecule and selection on the CCR5 gene may shed light on its functional role. The comparison of differences between intraspecific polymorphisms and...

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Intra- and interspecific variation of the CCR5 gene in higher primates.

Abstract excerpt

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Intra- and interspecific variation of the CCR5 gene in higher primates.

Abstract excerpt

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