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Article

Sex chromosome complement regulates expression of mood-related genes

7 Nov 2013

Abstract excerpt

BACKGROUND: Studies on major depressive and anxiety disorders suggest dysfunctions in brain corticolimbic circuits, including altered gamma-aminobutyric acid (GABA) and modulatory (serotonin and dopamine) neurotransmission. Interestingly, sexual dimorphisms in GABA, serotonin, and dopamine systems are also reported. Understanding the mechanisms behind these sexual dimorphisms may help unravel the biological bases...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Hypothalamic control of reproductive hormones
Neurotransmitter Receptor Influence on Behavior

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24199867
DOI: 10.1186/2042-6410-4-20

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