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Article

Possible association between a haplotype of the GABA-A receptor alpha 1 subunit gene (GABRA1) and mood disorders.

Biological psychiatry - 1 Jan 2004

Horiuchi Yasue, Nakayama Junko, Ishiguro Hiroki, Ohtsuki Tsuyuka, Detera-Wadleigh Sevilla D, Toyota Tomoko, Yamada Kazuo, Nankai Masahiro, Shibuya Haruo, Yoshikawa Takeo, Arinami Tadao

Abstract excerpt

BACKGROUND: The gamma-aminobutyric acid (GABA) neurotransmitter system has been implicated in the pathogenesis of mood disorders. The GABRA1 gene encodes one of the subunits of GABA-A receptor and is located on human chromosome 5q34-q35, which is a region reportedly linked to mood disorders. We examined the GABRA1 gene as a candidate for mood disorders. METHODS: We performed mutation screening of GABRA1 in 24...

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Source

Identifiers

PMID: 14706423
DOI: 10.1016/s0006-3223(03)00689-9

Genes

GABRA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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