Article
LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta.
Human molecular genetics - 15 Oct 2003
Traherne James A, Hill Michael R, Hysi Pirro, D'Amato Mauro, Broxholme John, Mott Richard, Moffatt Miriam F, Cookson William O C M
Abstract excerpt
Polymorphisms in the beta chain of the high affinity receptor for IgE (Fc epsilon RI-beta, MS4A2) are consistently associated with traits underlying asthma and atopy (immunoglobulin E-mediated allergy). However, the causal variants and haplotypes underlying disease have not yet been identified. Maternal effects, with association confined to maternally derived alleles, have been shown in some studies but not in...
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