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Article

Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy.

Allergy - 1 Mar 2013

Michel S, Busato F, Genuneit J, Pekkanen J, Dalphin J-C, Riedler J, Mazaleyrat N, Weber J, Karvonen A M, Hirvonen M-R, Braun-Fahrländer C, Lauener R, von Mutius E, Kabesch M, Tost J

Abstract excerpt

BACKGROUND: Genetic susceptibility and environmental influences are important contributors to the development of asthma and atopic diseases. Epigenetic mechanisms may facilitate gene by environment interactions in these diseases. METHODS: We studied the rural birth cohort PASTURE (Protection against allergy: study in rural environments) to investigate (a) whether epigenetic patterns in asthma candidate genes are...

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Source

Identifiers

PMID: 23346934
DOI: 10.1111/all.12097

Genes

RAD50
STAT6
FOXP3
ORMDL1
RUNX3
ORMDL2
ORMDL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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