Article
Cross-genetic determination of maternal and neonatal immune mediators during pregnancy.
Genome medicine - 22 Aug 2018
Traglia Michela, Croen Lisa A, Jones Karen L, Heuer Luke S, Yolken Robert, Kharrazi Martin, DeLorenze Gerald N, Ashwood Paul, Van de Water Judy, Weiss Lauren A
Abstract excerpt
BACKGROUND: The immune system plays a fundamental role in development during pregnancy and early life. Alterations in circulating maternal and neonatal immune mediators have been associated with pregnancy complications as well as susceptibility to autoimmune and neurodevelopmental conditions in later life. Evidence suggests that the immune system in adults not only responds to environmental stimulation but is...
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