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Article

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

The Journal of biological chemistry - 7 Nov 2003

Chen Hui, Montagnani Monica, Funahashi Tohru, Shimomura Iichiro, Quon Michael J

Abstract excerpt

Adiponectin is secreted by adipose cells and mimics many metabolic actions of insulin. However, mechanisms by which adiponectin acts are poorly understood. The vascular action of insulin to stimulate endothelial production of nitric oxide (NO), leading to vasodilation and increased blood flow is an important component of insulin-stimulated whole body glucose utilization. Therefore, we hypothesized that...

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PMID: 12944390
DOI: 10.1074/jbc.M307878200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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