Article
eNOS plays a major role in adiponectin synthesis in adipocytes.
American journal of physiology. Endocrinology and metabolism - 1 Apr 2010
Koh Eun Hee, Kim Mina, Ranjan K C, Kim Hyun Sik, Park Hye-Sun, Oh Ki Sook, Park In-Sun, Lee Woo Je, Kim Min-Seon, Park Joong-Yeol, Youn Jang Hyun, Lee Ki-Up
Abstract excerpt
Nitric oxide (NO) stimulates mitochondrial biogenesis. We recently reported that adiponectin synthesis is regulated by mitochondrial function in adipocytes. This study was undertaken to test the hypothesis that endothelial NO synthase (eNOS) plays an important role in adiponectin synthesis by producing NO and enhancing mitochondrial function in adipocytes. We examined the effects of eNOS knockdown on adiponectin...
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