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Article

Iron requirement for GAL gene induction in the yeast Saccharomyces cerevisiae.

The Journal of biological chemistry - 31 Oct 2003

Shi Xiaoli, Chabarek Kate, Budai Alice, Zhu Zhiwu

Abstract excerpt

Iron is an essential nutrient. Its deficiency hinders the synthesis of ATP and DNA. We report that galactose metabolism is defective when iron availability is restricted. Our data support this connection because 1) galactose-mediated induction of GAL promoter-dependent gene expression was diminished by iron limitation, and 2) iron-deficient mutants grew slowly on galactose-containing medium. These two defects...

Topics

Cell Division
Galactose
Gene Deletion
Iron
Mutation
Promoter Regions, Genetic
Saccharomyces cerevisiae

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12944385
DOI: 10.1074/jbc.M307011200

Genes

GAL

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