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Article

Oncolytic virus therapy using genetically engineered herpes simplex viruses.

Human cell - 1 Sept 2002

Todo Tomoki

Abstract excerpt

An increasing number of oncolytic virus vectors has been developed lately for cancer therapy. Herpes simplex virus type 1 (HSV-1) vectors are particularly useful, because they can be genetically engineered to replicate and spread highly selectively in tumor cells and can also express multiple foreign transgenes. These vectors can manifest cytopathic effect in a wide variety of tumor types without damaging normal...

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PMID: 12703545
DOI: 10.1111/j.1749-0774.2002.tb00109.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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