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Article

Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma.

28 Feb 1995

Abstract excerpt

Genetically engineered viruses and viral genes inserted into retroviral vectors are increasingly being considered for experimental therapy of brain tumors. A primary target of these viruses and vectors is human gliomas, the most frequently occurring primary human brain tumor. To investigate the potential of genetically engineered herpes simplex viruses (HSVs) in the therapy of these tumors, we compared the...

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Identifiers

PMID: 7877992
DOI: 10.1073/pnas.92.5.1411

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Source receipt: pubmed, retrieved 7 Sept 2026.

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