Article
Analysis of single nucleotide polymorphisms in the region of CLDN2-MORC4 in relation to inflammatory bowel disease.
World journal of gastroenterology - 14 Aug 2013
Söderman Jan, Norén Elisabeth, Christiansson Malin, Bragde Hanna, Thiébaut Raphaele, Hugot Jean-Pierre, Tysk Curt, O'Morain Colm A, Gassull Miquel, Finkel Yigael, Colombel Jean-Frédéric, Lémann Marc, Almer Sven
Abstract excerpt
AIM: To investigate a possible genetic influence of claudin (CLDN)1, CLDN2 and CLDN4 in the etiology of inflammatory bowel disease. METHODS: Allelic association between genetic regions of CLDN1, CLDN2 or CLDN4 and patients with inflammatory bowel disease, Crohn's disease (CD) or ulcerative colitis were investigated using both a case-control study approach (one case randomly selected from each of 191 Swedish...
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