Article
Alpha B-crystallin is not a dominant peripheral T-cell autoantigen in multiple sclerosis amongst Sardinians.
European journal of neurology - 1 Sept 2003
Sotgiu S, Pugliatti M, Contu S, Sanna A, Sgaramella E, VanNoort J M, Rosati G
Abstract excerpt
The heat shock protein alpha B-crystallin appears to be the dominantly recognized autoantigen in the early demyelinative process of multiple sclerosis (MS) in brain of patients. In Sardinia, MS is linked to human leucocyte antigen (HLA)-DR alleles that might influence the production of cytokines...
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