Genetic susceptibility to multiple sclerosis in Sardinians: an immunological study.

doi:10.1111/j.1600-0404.1998.tb01740.x

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Article

Genetic susceptibility to multiple sclerosis in Sardinians: an immunological study.

Acta neurologica Scandinavica - 1 Nov 1998

Sotgiu S, Serra C, Marrosu M G, Dolei A, Pugliatti M, Murgia B, Aiello I, Rosati G

Abstract excerpt

OBJECTIVES: We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS: ELISA w...

Topics

Cytokines
Enzyme-Linked Immunosorbent Assay
Female
Genetic Predisposition to Disease
HLA-DR Antigens
Humans
Leukocytes, Mononuclear
Male
Multiple Sclerosis

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