Article
Genetic susceptibility to multiple sclerosis in Sardinians: an immunological study.
Acta neurologica Scandinavica - 1 Nov 1998
Sotgiu S, Serra C, Marrosu M G, Dolei A, Pugliatti M, Murgia B, Aiello I, Rosati G
Abstract excerpt
OBJECTIVES: We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS: ELISA were used for detection of cellular products by mitogen-activated peripheral blood mononuclear cells. RESULTS:...
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