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Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus

1 Oct 2002

Abstract excerpt

An important feature of central nervous system (CNS) immune privilege is that antigens expressed in CNS are sequestered and not available for central tolerance induction. Tissue distribution and, more specifically, thymic expression of many of the CNS putative autoantigens have not yet been clearly established in humans. We have addressed this question for the putative multiple sclerosis(MS) autoantigens...

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PMID: 12355425
DOI: 10.1002/1521-4141(2002010)32:10<2737::aid-immu2737>3.0.co;2-0

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