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Article

The IκB Function of NF-κB2 p100 Controls Stimulated Osteoclastogenesis

25 Aug 2003

Abstract excerpt

The prototranscription factor p100 represents an intersection of the NF-kappaB and IkappaB families, potentially serving as both the precursor for the active NF-kappaB subunit p52 and as an IkappaB capable of retaining NF-kappaB in the cytoplasm. NF-kappaB-inducing kinase (NIK) controls processing of p100 to generate p52, and thus NIK-deficient mice can be used to examine the biological effects of a failure in...

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PMID: 12939342
DOI: 10.1084/jem.20030116

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The IκB Function of NF-κB2 p100 Controls Stimulated OsteoclastogenesisPMID 12939342Read ↗

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