Article
Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1).
Cell death and differentiation - 1 Dec 2003
Houseweart M K, Vilaythong A, Yin X-M, Turk B, Noebels J L, Myers R M
Abstract excerpt
Apoptosis can be mediated by mechanisms other than the traditional caspase-mediated cleavage cascade. There is growing recognition that alternative proteolytic enzymes such as the lysosomal cathepsin proteases can initiate or propagate proapoptotic signals, but it is currently unclear how catheps...
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