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Article

Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator.

Current biology : CB - 19 Aug 2003

Lewis Julian

Abstract excerpt

BACKGROUND: The pattern of somites is traced out by a mechanism involving oscillating gene expression at the tail end of the embryo. In zebrafish, two linked oscillating genes, her1 and her7, coding for inhibitory gene regulatory proteins, are especially implicated in genesis of the oscillations, while Notch signaling appears necessary for synchronization of adjacent cells. RESULTS: I show by mathematical...

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Identifiers

PMID: 12932323
DOI: 10.1016/s0960-9822(03)00534-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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